Effects of nutraceuticals on antibiotic efficacy: a scoping review

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Ikhwan Yuda Kusuma, Muhammad Iqbal, Edza Aria Wikurendra, Novera Herdiani

2024 CYTA - Journal of Food Vol. 22 Issue 1 Review Cited by 3 Quartile

Abstract

Interaction between nutraceuticals and antibiotics has attracted increasing interest as a potential approach to improve antibiotic efficacy. This scoping review aims to provide a comprehensive overview of the existing literature on the effects of nutraceuticals on antibiotic efficacy. An information specialist executed a multi-database search following the PRISMA-2020 guidelines to find articles published between 1 January 2013, and 1 April 2023. The addition of nutraceuticals to antibiotic treatments has shown promising results, for urinary tract infections, the supplementation of vitamin E alongside antibiotics significantly reduced the frequency of fever and urinary symptoms. In patients with hidradenitis suppurativa, the combination of MI, folic acid, and liposomal magnesium improved the efficacy of concurrent therapies and metabolic profiles. Immune manipulation with a nutraceutical alongside antibiotics proved effective and safe in reducing symptoms over time. These findings highlight the potential of nutraceutical addition to antibiotics in improving patient outcomes. © 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.

Affiliations

Pharmacy Study Program, Faculty of Health, Universitas Harapan Bangsa, Purwokerto, Indonesia; Institute of Clinical Pharmacy, Faculty of Pharmacy, University of Szeged, Szeged, Hungary; Department of Clinical Nutrition, Faculty of Health Science, Politeknik Negeri Jember, Jember, Indonesia; School of Food Science and Nutrition, University of Leeds, Leeds, United Kingdom; Doctoral School in Management and Organizational Science, Faculty of Economy Science, Hungarian University of Agriculture and Life Science, Kaposvár, Hungary; Department of Public Health, Faculty of Health, Universitas Nahdlatul Ulama Surabaya, Surabaya, Indonesia; Doctoral Program of Public Health, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia

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